Find out how to use Forskolin to gain mass and burn fat, due to which the substance significantly accelerates the metabolism of fats, as well as many other properties of the drug. Forskolin is made from the Coleus plant, the healing properties of which have been known for more than one millennium. Today, forskolin has become an integral part of a large number of thermogetics and fat burners. It was also scientifically found that forskolin increases life expectancy and inhibits the aging process, due to its effects on the work of the heart, arterial and respiratory systems.
Forskolin properties
Forskolin accelerates the synthesis of thyroid hormones and has a stimulating effect on the production of thyroid hormones. The metabolism-enhancing properties of these hormones have long been known. However, the positive effect on the body of forskolin does not end there. Traditional healers of India have been using forskolin for many centuries to treat diseases of the cardiovascular system, abdominal pain, insomnia, eczema, etc. Numerous studies have shown that the substance affects various processes in the human body due to its ability to activate a unique mechanism - cAMP or cyclic adenosine monophosphate …
TsAMP can be safely called the main signaling mediator that takes an active part in the regulation of intracellular processes. Thanks to cAMP, various enzyme systems are activated in the body and chemical reactions take place. The production of cAMP begins when the receptors of the cell membranes are stimulated by certain hormones, for example, adrenaline. After the hormone and the receptor enter into a bond, adenylate cyclase is activated, which synthesizes cAMP.
Forskolin is able to independently act on cell receptors without waiting for hormones. Actually, the properties of a fat burner are associated with this, which made it possible to use forskolin for gaining mass and burning fat. It is also well established that a substance is capable of influencing various physiological processes using other mechanisms. Scientists are now working to identify the receptors with which forskolin has the ability to bind.
It should also be said about the ability of forskolin to counteract platelet activation, due to the effect on the corresponding receptors. Platelet activating factor (PAF) plays an important role in the development of various inflammatory and allergic reactions. PAF is also involved in the activation of neutrophils, increases the permeability of blood vessels, can cause contraction of smooth muscles and reduce coronary blood flow. In one of the experiments, the platelet mass was first exposed to forskolin, and then PAF. As a result, scientists have identified an almost forty percent decrease in PAF activity when binding to cellular receptors. This suggests a decrease in the possible physiological response of platelets, which is induced by PAF.
Due to its ability to influence the synthesis of cAMP, forskolin has the following properties:
- Inhibits platelet activating factor;
- Inhibits the production of histamine;
- Increases the strength of contraction of the muscles of the heart;
- Has a positive effect on the walls of blood vessels and smooth muscles;
- Increases insulin production;
- Stimulates the thyroid gland;
- Increases the rate of breakdown of fat cells.
Now, after numerous studies, we can say that the areas of application of the substance are very wide. Due to the numerous unique properties of the substance, it is possible not only to use forskolin for weight gain and fat burning, but also for the treatment of many diseases, as well as their prevention.
The use of forskolin
In people suffering from allergic diseases, such as eczema, the level of cAMP in the cells of the skin and smooth muscles decreases, and at the same time the concentration of PAF increases. Due to the resulting imbalance of these substances, degranulation of mast cells begins to occur, which as a result leads to spasms of smooth muscles. This can be avoided by increasing cAMP levels.
It is thanks to the ability of forskolin to affect the synthesis of cAMP, bypassing the hormonal system, that the drug has become indispensable in the treatment of allergic diseases. It should also be noted the high anti-inflammatory properties of the substance, which have an effect on smooth muscles. This feature of forskolin was discovered by traditional healers in very ancient times. Forskolin can be successfully used both in solo use and in combination with other drugs.
It should be recognized that the mechanisms described above have certain differences when they directly affect cell receptors. Due to this feature, forskolin is successfully used in the treatment of bronchial asthma. Especially in this regard, the extract of the Coleus plant is effective, due to the ability of smooth muscles to relax under the influence of cAMP.
Forskolin dosages
Coleus roots contain about 0.2-0.3 percent, which is clearly not enough to obtain the expected therapeutic effect. But when using an extract containing concentrated forskolin, the results will be positive. Research on the substance continues today, which will make it possible to say more accurately about the dosage of the substance in the future. However, at the moment, the recommended dose of Coleus extract is 50 milligrams. This amount of extract contains about 9 grams of active substance. This dose should be taken twice or thrice throughout the day.
Watch a video review of Forskolin:
