Useful properties, indications and contraindications for the use of Adapalena. Instructions for use and side effects.
Types of drugs with Adapalene
Adapalene is a fourth generation retinoid. This substance is the only one in its group that is completely different from retinoic acid derivatives. All typical generation 1-3 retinoids have been shown to be excellent in the treatment of acne and acne. But, like most vitamin preparations, they can cause an allergic reaction.
Adapalene, unlike all retinol derivatives, is the result of the breakdown of naphthoic acid. Thanks to this, the substance is better absorbed and gives off more useful particles. In addition, the bonds of naphthoic acid in the molecule are weaker, respectively, the element reacts faster with free radicals and amino acids.
Overview of drugs based on Adapalene:
- Adaklin … The drug is sold in the form of a cream and gel. The composition of these substances is the same, they differ only in consistency. The gel is absorbed faster, and the skin does not get greasy and does not remain sticky. The drug is sold in tubes weighing 30 g, the concentration of the active substance is 1 mg / g. Manufactured in India. The cost of a 30 g tube is $ 12.
- Adolen … This is also a gel, the active ingredient of which is Adapalene. The concentration of the active substance is 0.1%. Adolen is sold in tubes of 5, 10, 15 and 30 g. The cost of a 15 g tube is approximately $ 5. The substance has a pleasant and non-greasy consistency. Produced by the famous Russian pharmaceutical company Sintez.
- Differin … A preparation containing Adapalene in an amount of 0.1%. The substance has a pleasant aroma. The consistency of the drug is rather viscous, which allows saving the medicine. Produced by Galderma in Moscow. On the shelves in the pharmacy you can see Differin cream and gel. The gel is recommended for those with oily skin, and the cream is ideal for patients with very dry epidermis. The cost of the drug is quite high, since Adapalene is a fourth generation retinoid. This is a novelty on the market and it is expensive to synthesize an active ingredient. The cost of the drug 30 g is 15 dollars.
- Klenzit C … The drug is sold in the form of a gel containing 0.1% Adapalene and Clindamycin. Due to the presence of the antibiotic Clindamycin, it is possible to reduce the activity of pathogenic and opportunistic organisms. With this gel, you can quickly get rid of acne. In this case, there is no need to use antibiotic-based drugs. Accordingly, it is better to use it for those who have oily epidermis. The gel does not spread and is quickly absorbed without leaving any greasy residue. The tool is quite expensive, the cost of a 15 g tube is $ 20. Klenzit is produced in India.
Instructions for the use of Adapalena for acne and acne
The drug is quite simple to use. The instructions indicate that the gel or cream should be applied daily. But some dermatologists recommend applying the drug in small portions at regular intervals.
Instructions for using drugs based on Adapalene:
- It is necessary to remove the remnants of cosmetics in the evening, it is best to do this with a neutral cosmetic product. Milk or cream is ideal. Never wash your face with soap or cosmetic remover. These substances contain alkali and dry the skin, respectively, by the time Adapalene is applied, the epidermis may be irritated.
- Then apply a small amount of cream or gel to your finger. Spread the preparation on the face using the dotted method.
- After that, rub the medicine along the massage lines. Allow the substance to completely absorb.
- Dermatologists recommend starting to use Adapalene 2-3 times a week. After two weeks, you can safely switch to the daily use of a cream or gel.
- It is also necessary to cancel the medicine smoothly, gradually reducing the frequency of its use. Never apply Adapalene several times a day. This can cause an allergic reaction.
The first results are already visible after 4-9 weeks of use. To achieve a stable therapeutic effect, the drug must be used for at least 3-4 months. After stopping the medication, acne may reappear.
Note! It is necessary to apply the drug before bedtime. After that, you should not go outside. This will encourage re-contamination of the skin.
Features of using Adapalena
It is worth noting that there are many subtleties associated with the use of Adapalen. This substance can react with alcohol or alkali.
Special instructions for the use of Adapalena:
- Do not use this product after using soap or shower gel. During this period, the epidermis can already itch and be irritated.
- After applying the product, do not go to the solarium or sunbathe on the beach. Adapalene makes the cover susceptible to ultraviolet radiation.
- Do not use lotions containing alcohol or acids together with Adapalene. These cosmetics can dry out the skin and cause irritation. Itching or irritation may occur with the use of this substance.
- In no case, after Adapalene, do not apply decorative cosmetics. Only in the morning you can make a make-up. Adapalene can react with substances that make up the powder or foundation.
- After applying the product, it is advisable not to take a shower or wash. Otherwise, you may wash off some of the gel or cause irritation.
- Do not use the medicine after exfoliating or scrubbing your skin. This can cause itching, redness and irritation.
- The combined use of Adapalene and antibiotics is permitted. But it is worth considering that the drugs must be applied at different times. This is due to insufficient information on the interaction of Adapalene with antibiotics. The drug is well combined with Clindamycin and Erythromycin. It is recommended to apply the antibiotic in the morning, and the Adapalene-based preparation in the evening.
- It is impossible to apply preparations containing sulfur, salicylic acid and perfume together with Adapalena. These substances contribute to the emergence of a cumulative, that is, a cumulative effect.
Side effects after using Adapalene
Subject to all the rules and conditions for applying the gel, side effects are extremely rare. Basically, irritation and an allergic reaction appear after improper use of the drug, when alcohol-containing substances are applied to the skin or sunbathing.
Before purchasing funds based on Adapalene, determine your skin type. It is advisable to apply a gel to the oily epidermis, and a cream to the dry epidermis. List of side effects after using Adapalena:
- Itching, burning, discomfort … With the right choice of cream or gel, this side effect is rare. It usually occurs after using soap and applying the product.
- Skin tenderness and swelling … This side effect may appear at the very beginning of the use of Adapalene. This is due to the interaction of the substance with sebum particles.
- Erythema and rash … Often occurs after using a large amount of the drug. Accordingly, it is necessary to apply a gel or cream in a very thin layer, so that the substance is only sufficient for absorption by the epidermis. That is, there should be no visible film on the face. This will lead to irritation and rash.
- Sunburn … This happens immediately after using Adapalene and sunbathing. After using Adapalena, more than 24 hours should pass. Only then can you sunbathe or visit the solarium. For the duration of treatment with the drug, refuse to travel to the sea or visit a solarium.
- Swelling of the eyelids or conjunctivitis … Try not to apply the drug to the eyelids and under the eyes. This can cause the eyelids to swell. Often the use of Adapalena is accompanied by itching in this area.
- Discoloration of the skin … Pigmented spots appear after using the drug and sunbathing. Adapalene can promote the accumulation of melanin in areas of maximum cream or gel application. That is why it is necessary to use the remedy with caution in patients with freckles and age spots.
How to use Adapalene for acne and acne - watch the video:
Adapalene is an effective synthetic drug, the action of which is similar to vitamin A. But, unlike it, the substance is better absorbed and helps to quickly get rid of acne.
