How is hormone replacement therapy performed after 50 years?

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How is hormone replacement therapy performed after 50 years?
How is hormone replacement therapy performed after 50 years?

Find out how to use steroids to the advantage of maintaining youth and vitality after 50 years. In medicine, two terms are often used that speak of an insufficient concentration of androgens in the male body: ADAM (androgen deficiency in an aging man) and PADAM (partial androgen deficiency in an aging man). Many people believe that testosterone is only necessary for regulating sexual function and achieving success in sports. However, in practice, this hormone is much more important for a man and, in fact, determines his state of health.

In many respects, the normal functioning of the liver, the metabolism of fats, the processes of hematopoiesis in the cellular structures of the bone marrow depend on the concentration of testosterone, normalizes the balance of lipoproteins, controls the level of sugar in the blood, etc. We will not now talk in detail about the functions that this hormone performs in the male body. To all of the above, we add only that in old age, due to testosterone deficiency, depression often develops and the work of the nervous system as a whole is inhibited, and brain activity also decreases.

When is hormone replacement therapy necessary after 50 years?

Pills in hand
Pills in hand

In medicine, the term "male menopause" was first introduced back in 1939 thanks to Dr. Werner. He described and substantiated the reasons for the appearance of a number of symptoms that appear in men after the age of fifty. Among the most significant were high nervousness, disturbed sleep patterns, increased sweating, hot flashes and a drop in sexual desire.

All of these symptoms are most active during sleep and immediately after awakening. It was at this time that the synthesis of the male hormone proceeds extremely weakly and as a result, its concentration falls below the normal value. Disorders of non-hormonal regulation are usually associated with age-related processes that lead to disruption of the reproductive system, as well as changes in body weight.

Secondary hypogonadism, which can cause a deficiency of the male hormone, is directly associated with impaired erectile function. It should be noted that the aging processes of our body are activated immediately after birth, but proceed at an extremely low rate. As they grow older, they accelerate, and the decline in the production of endogenous testosterone begins after 30 years. It is from this age that the male hormone is synthesized one percent slower every year.

According to numerous studies, it can be said that about a third of all men after 50 years of age experience a morning drop in testosterone concentration from normal levels in the amount of five percent. Testosterone in the male body, like estrogens in women, has some protective functions. In women, hormone replacement therapy after age 50 is used to relieve symptoms of menstrual irregularities, and has been extremely difficult for a long time. In the male body, with a decrease in testosterone concentration, such rapid disruptions in the body's work do not occur, as in women during menopause. It is this fact that is the reason for the postponement of hormone replacement therapy after 50 years in men. Moreover, this is also typical for those cases when therapy should have been started earlier. Note that between 50 and 60 years in the male body, the most significant biological changes occur.

Bs already at the beginning of the article spoke about two medical terms - ADAM and PADAM. However, they only apply to those men who are in the old age of 65. This is due to the fact that during this time most men stop working, and this leads to a decrease in activity. You must remember that it is physical activity that is the most effective way to fight the aging process.

Scientists studied the phenomenon of centenarians and came to the conclusion that they all worked intensively for a long time. Thus, hormone replacement therapy after 50 years is prescribed rather rarely and the generally accepted age for its implementation is from 65 years. At the same time, we noted that the rate of production of the male hormone begins to decline after 30 years.

The question of why exactly 65 years is considered to be the age when hormone therapy is needed is of interest to many. Perhaps you should not wait for the aging of the man, but start therapy earlier in order to maintain his health. Agree that the concept of "elderly person" is rather vague, because some men at 70 years old continue to remain active, both physically and sexually. At the same time, some already at 50 or a little later may be unable to endure even minimal physical activity.

Very often people are simply afraid to start hormone replacement therapy after 50 years, although its effectiveness is well known. The concentration of testosterone begins to decrease gradually and everyone can take preventive measures that will help you prolong your activity. First of all, you must be active and eat right.

How to carry out hormone replacement therapy for men?

Doctor and patient
Doctor and patient

Since the generally accepted age for starting the procedure is the age of 65 years, there is also an indicator of the concentration of the male hormone equal to 10 to 13 nmol / liter. If the testosterone level falls below this value, then hormone therapy is prescribed. But we have already found out that it may well be required earlier.

If symptoms of androgen deficiency are observed before the established age, then hormone replacement therapy after 50 years can also be carried out. Agree that today no one disputes the need to use, for example, exogenous insulin if necessary at any age.

In the male body, there cannot be a temporary sharp drop in testosterone concentration. At the same time, it would be logical to revise the dosage of testosterone-containing drugs that are used in hormone therapy. At the moment, the laboratory indicator of the normal content of testosterone is very wide and ranges from 17 to 40 nmol / liter. This suggests that it is also necessary to revise the methods of assessing the level of concentration of the male hormone.

It is quite obvious that all changes in the body are individual in nature and it is not entirely correct to use a general approach to all men in this situation. In our opinion, it will be more accurate to compare the testosterone concentration with those that took place at the age of 30–35. However, a completely natural question arises here - is it necessary to determine the level of testosterone in all men at this age?

Now for hormone replacement therapy after 50 years or at any other age, injectables containing synthetic male hormones are actively used. Tablets and even implants can also be used. However, they all often cause non-physiological changes in testosterone levels.

But this problem cannot be considered the most important. Under normal physiological conditions, various hormones are produced in Leyding cells. Let's find out what happens when artificial male hormone is used. First of all, it is necessary to note the drop in the concentration of luteinizing hormone. This, in turn, leads to a decrease in the production of hormones in the testicles and other hormones, not just male.

Today we know for sure that the process of testosterone production depends on LH. Simply put, if LH is synthesized at a normal rate, then the concentration of the male hormone remains high enough. As a result, we can say that for hormone replacement therapy after 50 years, it is worth using not testosterone-containing drugs, but those drugs that help accelerate the synthesis of LH. Such a remedy is chorionic gonadotropin.

Research on this drug as a hormone therapy has already been carried out. A group of men took gonadotropin for a month. Every 3rd or 4th day, they were injected with two thousand units of gonadotropin. As a result, the level of the male hormone has doubled at once! In addition, it must be said that all subjects after completing the course noted an improvement in their health.

But side effects after using gonadotropin were not observed, including the PSA indicator remained within normal limits. In the course of other studies, it was found that hCG also contributes to the elimination of erectile dysfunction, while increasing sex drive.

If oligospermia may develop when using drugs based on a synthetic male hormone, then after gonadotropin this does not happen. Moreover, the study participants noted an improvement in memory after a course of hCG. Today, most doctors are of the opinion that the main reason for the formation of androgen deficiency is a disruption in the work of the pituitary axis. But it is gonadotropin that can change this situation for the better.

However, hCG can be effective for hormone replacement therapy after 50 years only if the male body has not yet lost its ability to synthesize testosterone on its own. Otherwise, an exogenous hormone is indispensable.

For more on hormone replacement therapy in men, see the following video: